甘氨酸亚铁的合成工艺研究

论文编号:CL042  论文字数:11125,页数:27

摘 要：本文以氯化亚铁和甘氨酸为原料，研究了甘氨酸螯合铁的合成工艺条件。结果表明，pH值、配位比以及抗氧化剂用量对产品组成和得率有很大影响。确定了螯合的最适条件为：pH 值为5，配位比为2：1。采用有机溶剂萃取法，使甘氨酸螯合铁在无水乙醇中以沉淀的方式析出，实现甘氨酸螯合铁与无机铁的分离。讨论了萃取时有机溶剂用量对产品得率的影响，在无水乙醇与滤液的体积比为8：l时，亚铁得率最高。并用红外和DSC对产物进行分析表征。
 
关键词：甘氨酸；氯化亚铁；甘氨酸亚铁；

Abstract: The synthesizing conditions of ferrous glycinate chelate using ferrous chloride and glycine as raw materials were studied in this paper．The result showed that the constitution of the product and the recovery of ferrous were considerably affected by p H ，the molar ratio of glycine to ferrous, and the amount of antioxidant．The optimal reaction condition was pH 5.0，the molar ratio of 2：1．The filtrate was treated with organic solvent and the ferrous glycinate chelate was precipitated in ethyl alcohol absolute．Consequently，the chelate can be purified and analyzed by common chemical method． Extraction solvent was also evaluated． The effect of volume ratio of organic solvent to filtrate on the recovery of ferrous was studied． The highest recovery rate of ferrous was obtained at 8:1l of ethyl alcohol absolute to filtrate of ferrous glycinate. The product was characterized by IR and DSC.

Keywords：Glycine；ferrous chloride；ferrous glycinate

目  录

中文摘要 I
英文摘要 II
目录 III
1．绪论 1
   1.1甘氨酸螯合物的概述 1
       1.1.1 甘氨酸螯合物的定义及性质 1
       1.1.2 氨基酸螯合物的作用 2
   1.2甘氨酸螯合铁的概述 2
       1.2.1 铁的作用 2
       1.2.2 甘氨酸的作用 3
   1.3 甘氨酸亚铁的研究进展 3
       1.3.1甘氨酸螯合铁的发展及优势 3
       1.3.2 甘氨酸亚铁的合成 4
 1.4 立题目的和意义 6
2．实验部分 8
   2.1 实验试剂与仪器设备 8
       2.1.1 实验试剂 8
       2.1.2 仪器设备 8
    2.2 实验方法 9
       2.2.1 合成方案 9
       2.2.2 检测方法 9
3．结果与讨论 13
 3.1 铁源及萃取剂的选择 13
 3.2有机溶剂用量的选择 13
  3.3 PH值对反应的影响 14
　3.4抗氧化剂用量的选择 15
  3.5 配位比的影响 15
  3.6 红外谱图分析 16
  3.7 DSC分析 18
4．总结与展望 20
致谢 21
参考文献 22