Abstract: A new synthetic method of pyridine-benzylamine was described. A series of pyridine-benzylamines derivatives were synthesized by using amines and salicylaldehyde as the starting material， to produce the pyridine-benzylamines via a one-pot sequential process. The reaction of salicylaldehyde with amines stirring under room temperature will generate the benzyl amines. The reduction of benzyl amines was carried out by using soldium borohydride as reducing agent. After that, potassium carbonate and 2-Amino-4,6-dimethoxypyrimidine were added and heated to refluxing. After the mixture had been stirred for 7h with refluxing，the filtrate was evaporated to give the pyridine-benzylamine. The advantages of this method are high yield and simple work-up. Finally the structures of the compounds were determined by 1H NMR and LC-MS. The compounds were high efficiency postemergent herbicides for winter oilseed rape.
