This article is introduced The Simulation of Flexible manufacturing production line which include eight products. We should define the seven goods and the result of the assemble before the Simulation of Flexible manufacturing production. The three products we choose in this research are cannot offer from the MSN system. So we should product the goods by EXSL-WINsystem, then put them into the MSN. Second, we should decide some possible assemble program of production line. Afher the the teacher’s appraise, I make the last result. Then we can build the production line of assemble, this line include milling , lathing, transmission belt, axles, robots, work tableand goods. We should make them and take them to the fit sides. Last join belt and robot、milling machine and robot、lathe and robot by signal. Decide the robot’s position by the giving message. The end, we write the procedure according to the move process between robot and singnal by the robot procedure. Then test the system until finish it.