Abstract: In this dissertation, we mainly research on the reaction between indole and benzaldehydes catalyzed by NDPAT. In our research, we founded that NDPAT could efficiently catalyzed the reaction in ethyl acetate under room temperature . It was founded that the reaction rate between indole and benzaldehyde derivatives with electronic withdrawing group to the benzene ring was much faster than those with electronic donor group. Finally,the probable mechanism of the catalytic reaction has also been concluded according to this study.