Abstract: Chiral epichlorohydrin was a very important synton in organic synthesis. It was very common and easy to start with chiral epichlorohydirn for the generation and manufacturing of optically active compounds.Compared with some other methods, the hydrolytic kinetic resolution (HKR) was chosen for the production of (S)-epichlorohydrin. Condensation of (R,R)-1,2-Diammoniumcyclohexaneono-(+)-tartrate with 5-di-tert-butylsalicylaldehyde gave the chiral Salen ligand，which reacted with cobalt acetate and then oxidized to give the (Salen) Co(III) catalysts，which catalyzes the asymmetric ring-opening of racemic epoxides to afford epoxides with the ee up to 99％．Finally, three kinds of salen catalysts were synthesized, such as [(salen)Co(Ⅱ)]2(AlCl3)，[(salen)Co(Ⅱ)]2(FeCl3), [(salen)Co(Ⅱ)]2(ZnCl2). It was turned out that this two new kinds of catalysts can catalyzes epichlorohydrin availability, UV-vis absorption Spectra (Salen) Co(Ⅱ) and FeCl3, AlCl3and ZnCl2 which were measured mixing in CH2Cl2.
