Abstract : This article is about the determination of aspirin content with two methods. Aspirin is widely used, which can be commonly found in the combination of Chinese and Western rule prevailing cold preparations, and the effect is quitely obvious. For example, it plays a great role in analgesic, anti-inflammatory, antipyretic, antirheumatic and inhibittin platelet aggregation aspects. Non-steroidal anti-inflammatory drugs like aspirin, has always been regarded as relatively safe, a good symptomatic treatment drugs. The content determination of Aspirin is acid-base titration in many literatures, which is conditional in the actual application. In this article, we use two methods to determine the content of Aspirin. The two methods are UV spectrophotometry and HPLC. The results suggest that two methods all can determine the content of Aspirin. With comparison of the two methods, HPLC has separating and analytical functions, wider application of a strong specificity, high sensitivity Therefore HPLC is a more accurate determination of the content of aspirin.
