This topic is makes using the modern drugs manufacture technology the medicine the micro pill, fills again in the capsule, causes the medicine slow release. After contains medicine micro pill bond screening, slow release level prescription screening as well as the intestines dissolves level prescription screening, had determined the best technique of production route, and studied the slow release coating prescription, the intestines to dissolve the level prescription craft emphatically. The result indicated that this craft reasonable, is stable, is feasible. Studied and has formulated this preparation quality specification, has established the distinction, release's determination method separately, used the highly effective liquid phase chromatography determination hydrochloric acid handkerchief Rowsey sandbank intestines to dissolve in the slow release capsule the hydrochloric acid handkerchief Rowsey sandbank content, this standard gauge has the specificity to be strong and reproduction quality good characteristic. After the acceleration test 6 months and the long-term test 24 month stability inspection result indicated: Preparation basic stable.