Abstract
The modern medicine already steps into the times of the calculating medical science.One of the principal characters about current science study will be：all science experience the mathematic-rization course,making fodetermining the amounts of the components of a substance from determining the nature. Although the math-rization of immune system starting late, walk up to the health road and situation rectifying to be in the ascendant that become a hot spot problem which the medical science community shows solicitude for broadly. In this paper,the dynamics of antibody production and immune response to antigens are discussed. And the mathematic model of hepatitis B virus is reviewed．
Keywords：Mathematical model; Immune system; Immune response; Hepatitis B virus
