ABSTRACT
OBJECTIVE: This study is to compare rates of phlebitis and swelling caused by peripherally inserted central catheter (PICC) via ipsilateral and contralateral arms in breast cancer patients.
METHODS: A total of 147 breast cancer patients were randomly assigned to two groups: experimental group and control group. The experimental group received chemotherapy via PICC inserted in their ipsilateral arm to their cancer sites. The control group received chemotherapy in contralateral arm. This is to compare rates of phlebitis and swelling induced by the two different ways for PICC infusion of chemotherapy.
RESULTS: The rate of phlebitis induced by ipsilateral PICC is 16.7%, which is significantly higher than 5.3% of contralateral PICC (P < 0.05). The swelling rate of ipsilateral PICC is 26.4%, which is also significantly higher than 6.7% of contralateral PICC (P < 0.01). In comparison with the control group, there were more patients from the experimental group who had to switch to other ways of drug infusion(P < 0,05).
CONCLUSION: To better protect breast cancer patient's blood vessels, the ipsilateral arm should not be used as the first choice for the PICC infusion of chemotherapy.
关键词及定义
乳腺癌:乳腺恶性肿瘤。
外周置入中心静脉置导管(PICC):经外周静脉穿刺将导管置入中心静脉里(peripherally inserted central catheter)。
化疗:化学药物治疗法。
静脉炎:浅表静脉内膜炎症。
论文类型:类实验性研究。