With the development of globalization, business activities are more and more frequently. The concept of “cross-culture” has been flexibly used by many entrepreneurs for their enterprises in the world. Cross-culture business negotiation has become an important part of international business communication activity. Therefore, in order to effect the negotiation effectively and gain the win-win situation for both party, we must have a thorough understanding of different cultures, analyze the differences among the cross-culture thinking, and its influence on negotiation thinking. Through the embedded research on thinking style, we can distinguish the negotiation styles and skills of different cultures. The thesis is to elaborate the importance of negotiation thinking in the business negotiation, and the influence of the cultural differences upon the mode of thinking. In the passage, the positive and negative influence of the cultural differences for the business negotiation under the cross-cultural background is to be discussed. It mainly focuses on the differences of negotiation thinking, the acceptance of different culture, the caution is the business communication, the complication of negotiation and so on. Furthermore, some countermeasures for the cross-cultural negotiating are to be put forwarded. Such as, the establishment of relationship in different negotiation parties, the understanding of the policy procedure, attention to the legal environment of the dissimilarity nations, etc. The intention of the thesis is to provide certain theories instruction to the business negotiation practice.