In recent years, Chinese enterprises of export are affected by the 337 investigation of the United States Tariff Act, and the losses are very heavy. The paper starts with introducing an overview of the background and content of the 337 investigation of the United States Tariff Act, and then expatiates on the current situation, of which Chinese enterprises of export are affected by the 337 investigation of the United States Tariff Act, and explains why China would become one of the most important respondents, from the United States and China respectively. And then summarizes adverse effects about "Section 337" of the United States, mainly affecting the domestic industries of export to U.S., and some are even completely lost the U.S. market, and some have to pay high patent fees, and being not conducive to the upgrading of the structure of the export products, and so on. finally through the analysis of the main problems, of which Chinese enterprises of export deal with "337 investigation", and identify some countermeasure, by which deal with "337 investigation", such as: to enhance the capability of independent innovation and raise awareness of intellectual property protection; once involved, and responding actively; seek help associations and so on.