The scale of multinational corporations’ merger and acquisitions were constantly augmenting in China. Due to the difference between culture and system, multinational corporations still have some problems in post-merger integration. China , as the purchased market, has positive impact in importing technology and advanced managerial system and reforming enterprise by the way of cross-border merger and acquisitions, meanwhile it has negative impact in losing location brand, being monopolized , losing job and losing national resources. According to the China’s situation, comments and suggestions are concluded from policy, low, technology and company to try to reduce the negative impact.