This paper elaborates the domestic third-party logistics information development and researches the problems in the development from the perspective of third-party logistics information system, combined with the related theory. This article takes Zhejiang SF Express Co. Ltd as an example, analyzes the information construction, researches the problems in the information system of it. Based on the WEB-based third-party logistics information system, it reforms the information system of it combined with the development of the company. And it manages the core customer profiles with 8020 principle to allow the company to achieve the efficiency optimization. The designed information improves the efficiency of the original system and reduces the error rate. It allows the company to offer the client comprehensive functionality, reduce the cost while improving the corporate earning, increase economic efficiency and the domestic competitive advantage.