Abstract: This article introduces the right of shellfish toxins on the background and significance of the nerve shellfish poisoning the source of its hazards and a simple presentation and analysis of shellfish poisoning of the status quo, summed up some of the existing Neural shellfish toxin detection methods, the respective comparative advantages and disadvantages, and high-performance liquid chromatography - tandem mass spectrometry technology is the best detection method, high sensitivity and selectivity, susceptible to interference from other substances, Achieve good results. . In this paper, LC-MS/MS method of aquatic products in shellfish toxin domoic acid content was measured, with 50 percent methanol-water solution extraction, LC-SAX-through decontamination, and API3000-chromatography - Series triple quadrupole - Mass spectrometry analysis, with satisfactory results.
Key words: neural shellfish toxin; Domoic acid; high-performance liquid chromatography - tandem mass spectrometry
