Abstract：This article is mainly about the synthesis of aminated-pachymaran by using Yalpani method and the synthesis of carboxylmethyl-pachymaran by using one-step method. All derivatives were characterized by IR. The DS of the derivatives were calculated by elemental analysis and acid-base titration, respectively. The weight average molecular weight of carboxylmethyl-pachymaran was measured by LLS. Experimental results showed that aminated -pachymaran had the bile acid binding capacity. In addition, the DS of carboxylmethyl-pachymaran prepared using isopropanol as the reaction medium was higher than using ethanol as the reaction medium. Keywords：Pachymaran one-step Amination Carboxymethylation
