Customer is the ultimate of all elements of business operations, customer relationship management, e-commerce site is directly related to competitive advantage. In this paper, analysis based on literature data, combined with domestic and international development related sites, e-commerce site on the customer relationship management on a more thorough and systematic study. Articles from e-commerce and customer relationship management theory Introduction to the Theory starting of a new connotation between the two; and then discussing the e-commerce environment, the business use of information technology, through meaningful communication to understand and influence customer behavior, increase customer recruitment rates, customer retention, customer loyalty and customer profitability. Finally, online bookstores such a case study of customer relationship management on the importance of e-commerce sites.