Title: Effects of parenteral nutrition combined with enteral feeding on premature infants' physical development.
Abstract
Objectives: To explore the effects of parenteral nutrition combined with enteral feeding on premature infants' physical development.
Methods: 90 cases of premature infants in the neonatal intensive care unit of our hospital were randomly assigned into control group(group A),the observation group(group B).There are 45 cases in each group. All infants in the two groups received parenteral nutrition .At the same time ,the infants in group A received enteral nutrition according to 20mL / ( kg·d ) increasing milk quantity .While the infants in group B received enteral nutrition according to 30mL / ( kg·d ) increasing milk quantity. The birth weight, length, head circumference, Apgar score at 1 min,Apgar score at 5 min of all preterm infants were measured when they were born. The birth weight, length, head circumference of preterm infants in two groups were measured when they were 10 days old and one month old respectively.NBNA score of premature infants in two groups were measured when the corrected gestational age was 40 weeks.Record the cases of related complications in two groups and their relevant clinical indexes.
Results：There were no ssignificant differences between the two groups in the gender, gestational age, birth weight, length,head circumferenc, 1 minute Apgar score, Apgar score at 5 min. The weight change tendency of two groups in 10 days are similar, but after 4 days the rising amplitude in the observation group was greater than that of the control group, more rapid recovery to levels at birth;The body weight of the observation group was higher than that of the control group in the tenth day, but the difference was not significant ( P > 0.05 ). The body weight in the observation group was significantly higher than that in the control group when they were one month old, the difference was statistically significant ( P < 0.05 ).When they were 10 days old,one month old,the length in the observation group was higher than that of the control group, but the differences were not statistically significant ( P
> 0.05 ). When they were 10 days old,one month old, the head circumference in the observation group was higher than that of the control group,there was also no significant difference.When the corrected gestational age was 40 weeks , passive muscle tension, capacity of active muscle tone, primitive reflexes score of premature infants in the observation group were higher than those in the control group, the difference was statistically significant ( P < 0.05 ). When the corrected gestational age was 40 weeks, the general assessment score of the observation group was not statistically significant compared with the control group( P >0.05 ). When the corrected gestational age was 40 weeks, the NBNA score in the observation group was higher than the control group, there were significant differences between the two groups ( P < 0.05 ). There were no significant differences between the two groups in feeding intolerance , hyperbilirubinemia, apnea and the incidence of NEC during the hospitalization period( P >0.05 ). The time of reaching full enteral feeding , the time of reaching the birth weight, the duration of parenteral nutrition, duration of hospital stay and hospital costs of the observation group were lower than the control group, the differences were statistically significant( P < 0.05 ).
Conclusion:1 Parenteral nutrition plus 30mL / ( kg·d ) feeding amount can promote the growth of body weight of premature infants.
2 Parenteral nutrition plus 30mL / ( kg·d ) feeding amount dose not increase the feeding associated complications of premature infants, especially does not increase the incidence of NEC.
3 Parenteral nutrition plus 30mL / ( kg·d ) feeding amount can promote the premature infants to achieve full enteral feeding as soon as possible and shorten the recovery of birth weight and the duration of parenteral nutrition.
Key Words：premature infants；parenteralnutrition；enteral nutrition
Type Of Thesis: Applied Research
