Study on the Oxidation of Pachymaran and Its Biological Activity
Abstract: This paper introduces the oxidation of pachymaran and its biological activity. During the preparation of the oxidation of pachymaran. TEMPO was used and then transform infrared spectroscopy was used to characterize the structure of oxidation product. At the same time, the biological activity of derivative was tested. According to furfural cuvette method, it was found that oxidation of pachymaran of bile acid binding capacity is higher than that without the chemical modification of pachymaran, but the overall bile acid binding capacity is not high. Using Feton reaction produces hydroxyl radical, it was found that oxidation of pachymaran have the effect of clearance to hydroxyl radical. In the free radical scavenging capacity test, it was found that the oxidation of pachymaran have some OH- hydroxyl radical and superoxide radical scavenging ability.
Key words: Pachymaran; Oxidation of pachymaran; FT-IR; Bile acid binding capacity; Free radical scavenging capacity;